Isoflurane versus Desflurane for Anaesthesia in Surgical Operation: A Comparison of Maintenance and Hemodynamic Profile

Abstract

Background: Inhaled volatile anesthetics continue to be the most extensively used drugs for maintenance of general anesthesia because of their ease of administration and predictable intraoperative and recovery characteristics. The aim of this study was to assess the use of Isoflurane and desflurane during operation. Methods: In this study, a total of 58 patients were included whom undergo surgery in governmental hospitals in Tripoli, Libya. All cases were assessed for the use of anesthesia gases (types, duration, and any possible side effect). Brief information about the study, the subject information and the type of operation was taken and recorded in specific form during the study. Results: Our result have found that 51.7% of patients were males, while 48.3% of patients were female. The study subjects were predominated by Libyans in both genders. The main age of male was 28.2%, while the main age of female patients was 30%. There were 20% patients were undergo orthopedic operation, while 80% were surgical operation. We have also found that desflurane has been given to patients with median dose 2.08 MAC twice during operations, in compare to isoflurane 1.6 MAC twice during operation. The main duration of action of desflurane was 8.3 min, while the main duration of action of isoflurane was 7.8 min. Conclusion: The results in this study found that isoflurane has been used more frequently than desflurane, with dose of 1.6 MAC and 2.08 MAC of isoflurane to desflurane respectively. The duration of action was longer with isoflurane usage than with desflurane. Both of the inhalation gases have been used twice during the operation time, and no side effects has been reported in this study with the use of both agents.